Avengers: Infinity War squashes Life of the Party and Breaking In at box office 

With all due respect to Melissa McCarthy and Gabrielle Union: It’s Thanos’ world, we just live in it.

In its third weekend, Disney and Marvel’s superhero blockbuster

continues to dominate the box office, earning an estimated $61.8 million from 4,474 theaters in the U.S. and Canada while trouncing McCarthy’s new comedy

cracked the $500 million mark at the domestic box office, becoming the second-fastest film to do so, and through Sunday it will have grossed about $547.8 million. The movie also bowed in China this weekend, powering a massive $281.3 million international haul. Its worldwide total now stands at about $1.6 billion and ranks fifth all time, behind 

Directed by Joe and Anthony Russo and made for close to $300 million, 

film and the 19th installment of the Marvel Cinematic Universe. It features heroes from across the MCU franchise — including Robert Downey Jr.’s Iron Man, Chris Evans’ Captain America, Scarlett Johansson’s Black Widow, Tom Holland’s Spider-Man, and the Chris Pratt-led Guardians of the Galaxy — and pits them against Thanos (Josh Brolin), an interplanetary warlord trying to wipe out half the life in the universe.

An untitled sequel is already on the calendar for May 3, 2019.

will take in about $18.5 million at 3,656 domestic theaters. That figure is in line with industry projections but falls short of recent

Written by McCarthy and her husband, Ben Falcone, who also directed,

centers on a middle-aged divorcée (McCarthy) who returns to college to finish her degree and winds up in class with her daughter (Molly Gordon). The film received lackluster reviews from critics, and audiences gave it a tepid B CinemaScore.

, is on pace to gross about $16.5 million at 2,537 theaters, good for third place. That’s a solid start for a film that cost a modest $6 million to make.

), the film stars Union as a mother forced to protect her kids when the mansion of her recently deceased dad is invaded by burglars. Reviews have been poor, and moviegoers gave it a B CinemaScore.

Rounding out the top five this weekend are Lionsgate and MGM’s rom-com remake

, with about $10.1 million, and Paramount’s silently spooky horror hit

According to ComScore, overall box office is up 4.8 percent year-to-date. Check out the May 11-13 figures below.